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The key components of antibody-drug conjugates or ADCs include a monoclonal antibody (mAbs), a stable linker and a cytotoxic (anticancer) agent. Monoclonal antibodies are attached to biologically active drugs by chemical linkers with labile bonds. By combining the unique targeting of mAbs with the cancer-killing ability of cytotoxic drugs, antibody-drug conjugates allow sensitive discrimination between healthy and diseased tissue. Antibody-drug conjugates are part of a specialized and technicall

What are Antibody-drug Conjugates (ADCs)?

⏲ 2 min 13 sec ✓ 05-Feb-2016

Zero To Finals

How do monoclonal antibodies work? Rituximab, infliximab, adalimumab and others

⏲ 11 minutes 49 seconds 👁 370.4K

Dr. Rob Swanda

Monoclonal Antibodies (mAbs) & Covid-19

⏲ 2 minutes 👁 2.6K

Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells.nnThis may then stimulate the patient's immune system to attack those cells. It is possible to create a mAb specific to almost any extracellular/ cell surface target, and thus there is a large amount of research and development currently being undergone to create monoclonals for numerous serious diseases (such as rheumatoid arthritis, multiple sclerosis and different types of cancers). T

Monoclonal Antibody Therapy - Mode Of Action

⏲ 7 sec ✓ 04-Jul-2011

FuseSchool - Global Education

Monoclonal Antibodies | Health | Biology | FuseSchool

⏲ 3 minutes 57 seconds 👁 129.3K

Hussain Biology

Monoclonal Antibodies and its Production

⏲ 3 minutes 32 seconds 👁 86.9K

Antibody Drug Conjugate (ADCs) killing mouse breast cancer cells. Left: antibody isotype non-specific for mouse breast cancer cells. Right: antibody specific for mouse breast cancer cells. nnOne of the main limitations associated with standard chemotherapy is the unspecific killing of healthy cells (e.g. rapidly dividing cells in the bone marrow) which is associated with high-dose requirement and low therapeutic indices.nnIn order to significantly reduce systemic side effects, it is fundamental

Antibody Drug Conjugate (ADCs) killing mouse breast cancer cells

⏲ 64 sec ✓ 17-Jun-2019

VJHemOnc – Video Journal of Hematology u0026 HemOnc

Monoclonal antibodies in AML - current and future outlooks

⏲ 2 minutes 54 seconds 👁 63

NYCHealth

Monoclonal Antibodies (mAbs) for Treatment and Prevention of COVID-19

⏲ 56 minutes 27 seconds 👁 138

As the region’s health leader, Bayhealth is using new and innovative treatments to help in the fight against COVID-19. The latest tool is a limited supply of Food and Drug Administration (FDA) approved monoclonal antibodies (mAbs), the therapeutic agents designed to treat COVID-19 in high-risk patients. This treatment was authorized for emergency use by the FDA and has been distributed through the government to healthcare systems like Bayhealth. These synthetically created antibodies mimic the

Monoclonal Antibody Infusions at Bayhealth

⏲ 1 min 52 sec ✓ 26-Jan-2021

operones

Monoclonal Antibodies and Recombinant Antigens production | contract manufacturing

⏲ 2 minutes 6 seconds 👁 5.7K

Roche

Monoclonal antibodies in medicine

⏲ 4 minutes 46 seconds 👁 5.3K

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