_new-inhibitor-prevents-lesions-and-reduces-tumour-size-in-basal-cell-cancer.jpg "New inhibitor prevents lesions and reduces tumour size in basal cell cancer from ptch Video Screenshot Preview")
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⏲ Duration: 3 min 45 sec
✓ Published: 19-Jan-2018
✓ Published: 19-Jan-2018
Description:
A new hedgehog pathway inhibitor demonstrated efficacy in preventing and treating basal cell cancer among patients with basal cell nevus syndrome, a rare inheritable disease. It is known that basal cell nevus syndrome is caused by a mutation in the PTCH gene, which encodes a primary inhibitor of the hedgehog signalling pathway. Using this information, researchers developed the anti-hedgehog signalling pathway drug GDC-0449.nnnnDr Ervine Epstein discusses the extremely positive results of a Phase
A new hedgehog pathway inhibitor demonstrated efficacy in preventing and treating basal cell cancer among patients with basal cell nevus syndrome, a rare inheritable disease. It is known that basal cell nevus syndrome is caused by a mutation in the PTCH gene, which encodes a primary inhibitor of the hedgehog signalling pathway. Using this information, researchers developed the anti-hedgehog signalling pathway drug GDC-0449.nnnnDr Ervine Epstein discusses the extremely positive results of a Phase
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